NIHR163838: East Africa AMR-STOP: Strategies for Tackling, Optimising and Preventing Environmental AMR (AfricaAMR-STOP)

About this project

Research questions: (1) How do abiotic and biotic factors influence the levels and concentrations of antibiotics and antimicrobial resistance genes (ARGs) in aquatic environments? (2) How is environmental antimicrobial resistance (AMR) linked to human and animal health? (3) How can eco-hydro wetlands be optimised to remove antibiotics (ABs), ARGs and multidrug-resistant pathogens (MDRs) from wastewater? (4) What is the economic cost of AMR? (5) How can Community Engagement and Involvement (CEI) be enhanced to reduce AMR spread? (6) What capacity can be built for sustainable research and management of environmental AMR? Background: AMR is an urgent public health problem with a serious threat to human, animal and environmental health. It is particularly severe in Low- and Middle-Income Countries due to: (1) weak and disjointed monitoring and surveillance of AMR in the environment, (2) lack of technological advances to detect, assess and remove ABs, ARGs and MDRs from the environment, (3) scarcity of data on burden and drivers of AMR and surveillance, (4) limited data on economic cost of AMR, (5) lack of awareness, knowledge and enforcement of existing legislation, and (6) weak structures and lack of skilled human capacities in AMR research. Aims and objectives: We aim to co-develop a One Health approach to mitigate and manage environmental AMR for enhancing health and wellbeing in Kenya and Uganda. Our objectives are to: (1) investigate the influence of abiotic and biotic fact…

Goals

Sustainable Development Goals this project works towards

• 3Good Health and Well-being
• 6Clean Water and Sanitation

Published by

Manchester Metropolitan University · Academic, training and research

Countries

United Kingdom, Kenya, Uganda, South Africa

Sectors

Infectious disease controlBasic drinking water supply and basic sanitation

Funded by

National Institute for Health and Care Research

Implemented by

Masinde Muliro University of Science and Technology, Makerere University, Busitema University, University of Pretoria, South African Medical Research Council, Jaramogi Oginga Odinga Teaching & Referral Hospital, Kisumu Water and Sanitation Company Limited, National Environment Management Authority, Public Health and Sanitation- County Government of Kisumu, St. Mary's Hospital Lacor

Accountable

Manchester Metropolitan University

Published by Manchester Metropolitan University to the International Aid Transparency Initiative (IATI), last updated 2 Sept 2026 and imported automatically. IATI identifier: GB-UKPRN-10004180-1002274.

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