COGNITIVE THERAPY FOR DEPRESSION IN TUBERCULOSIS TREATMENT

About this project

COGNITIVE THERAPY FOR DEPRESSION IN TUBERCULOSIS TREATMENT We will develop CONTROL (COgNitive Therapy for depRessiOn in tubercuLosis treatment), a complex intervention consisting of 4 key elements: (i) screening for depression in TB patients using the Patient Health Questionnaire–2; (ii) a brief psychological intervention based on cognitive therapy principles consisting of six sessions; (iii) intervention delivery using a cascade model of training to train TB health workers to provide therapy; and (iv) Integration of mental health outcomes in TB control programme. The CONTROL research programme will be based in Pakistan targeting both Pakistan nationals and Afghan refugees living in Pakistan to develop and evaluate the CONTROL intervention and identify early implementation outcomes. The research programme will consist of four Work Packages (WPs): - WP 1. Developing intervention using evidence synthesis based on ethnographic and qualitative methods for incorporating the perspectives of patients, and care givers, and health professionals. WP 2. Inbuilt pilot RCT to test and refine intervention with a clear progression criterion to the definitive trial. WP 3. The definitive trial will test CONTROL versus Enhanced Treatment as Usual. The evaluation of intervention will consist of a combination of quantitative and qualitative methods, including a pragmatic RCT following a hybrid type-1 implementation approach. The primary effectiveness outcomes will include the decline of depress…

Published by

Academic, Training and Research · Academic, training and research

Countries

Pakistan

Sectors

Medical research

Funded by

Department of Health and Social Care

Implemented by

Healthnet Transcultural Psychosocial Organistaion, HealthNet TPO, Kyber Medical University, University of Sheffield

Accountable

Keele University

Published by Academic, Training and Research to the International Aid Transparency Initiative (IATI), last updated 11 Jun 2026 and imported automatically. IATI identifier: PK-NTN-9051408-4-CONTROL.

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