Developing bacteriocin-rich extract from engineered lactic acid bacteria as an antibiotic alternative in ruminants and aquaculture

About this project

Several compounds have been proposed in recent years as alternatives to antibiotics. Among them, antimicrobial peptides are one of the promising replacements for antibiotics, including those produced by bacteria called bacteriocins. However, the existing bacteriocins are subjected to costly purification procedures that are not feasible for application in low- and middle-income countries. This project, implemented in Nigeria, will develop a novel rapid and affordable technology to produce bacteriocin-rich extract as an alternative to antibiotics in ruminants and aquaculture. Field trials using this extract in therapeutic and prophylactic use against S. aureus and S. agalactiae infections in dairy ruminants and S. agalactiae infections in farmed tilapia will be done. The identification of the factors influencing the treatment of the infections and an assessment of the costs and benefits of using bacteriocin-rich extract will add to the findings and provide the basis for knowledge transfer and training in low- and middle-income countries. This project is funded through InnoVet-AMR2, a four-year partnership between IDRC and the United Kingdom’s Department of Health and Social Care. The initiative is aimed at reducing the emerging risk that antimicrobial resistance in animals poses to global health and food security.

Published by

International Development Research Centre · Other public sector

Countries

Nigeria

Sectors

Agricultural research

Published by International Development Research Centre to the International Aid Transparency Initiative (IATI), last updated 1 Sept 2026 and imported automatically. IATI identifier: XM-DAC-301-2-110337-003.

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